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Glucovance is indicated to manage blood sugar levels in patients with type 2 diabetes mellitus.

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The dosage is based on your medical condition and response to treatmentTo reduce your risk of side effectssuch as upset stomach and low blood sugaryour doctor may direct you to start this medication at a low dose and gradually increase your doseYour doctor will adjust your dose based on your blood sugar to find the best dose for youFollow your doctor’s instructions carefully.

A single-dosemetformin-furosemide drug interaction study in healthy subjects demonstrated that pharmacokinetic parameters of both compounds were affected by coadministrationFurosemide increased the metformin plasma and blood C max by 22and blood AUC by 15without any significant change in metformin renal clearanceWhen administered with metforminthe C max and AUC of furosemide were 31and 12smallerrespectivelythan when administered aloneand the terminal half-life was decreased by 32without any significant change in furosemide renal clearanceNo information is available about the interaction of metformin and furosemide when coadministered chronically.

Take this medication by mouth with meals as directed by your doctorusually once or twice a dayDrink plenty of fluids while taking this medication unless otherwise directed by your doctor.

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